96
6
239
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1674 |
Nateglinide
那格列奈,A4166,Senaglinide |
Potassium Channel; Proteasome; PPAR | DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome; Ubiquitination |
Nateglinide (Senaglinide) 是 D-苯丙氨酸的一种衍生物,是口服有效的、短效促胰岛素释放化合物,也是 DPP IV 抑制剂。 Nateglinide 抑制胰岛 β 细胞中 ATP 敏感的 K+通道。Nateglinide 在 2 型糖尿病中具有研究价值。 | |||
T25340 |
Diprotin A
Ile-Pro-Ile,抑二肽素A |
DPP-4 | Proteases/Proteasome |
Diprotin A (Ile-Pro-Ile) 是二肽基肽酶 IV (DPP-IV) 的抑制剂。 | |||
T36583 |
Gly-Pro-pNA hydrochloride
Gly-Pro p-nitroanilide hydrochloride |
Proteasome | Proteases/Proteasome; Ubiquitination |
Gly-Pro-pNA hydrochloride (Gly-Pro p-nitroanilide hydrochloride)是一种二肽基肽酶抑制剂,对二肽基肽酶II、二肽基肽酶IV和二肽基肽酶IX具有抑制作用。 | |||
T78410 |
Gly-Pro-AMC hydrobromide
Gly-Pro-AMC HCl |
||
Gly-Pro-AMC hydrobromide (Gly-Pro-AMC HCl) 为特异性荧光染料,用于细胞荧光检测,检测 Dipeptidyl peptidase IV (DPP-IV) 活性。 | |||
T4467 |
UAMC00039 dihydrochloride
UAMC 00039 dihydrochloride |
Proteasome | Proteases/Proteasome; Ubiquitination |
UAMC00039 dihydrochloride 是可逆、竞争性的 dipeptidyl peptidase II 高效抑制剂,IC50=为0.48 nM。 | |||
T67852 |
Linagliptin Methyldimer
|
Proteasome | Proteases/Proteasome; Ubiquitination |
Linagliptin Methyldimer 是一种强效的二肽基肽酶 IV 抑制剂,IC50=6 pM。 | |||
T29019 |
TS-021
TS021,TS 021,TS-021 Free |
DPP-4 | Proteases/Proteasome |
TS-021 是一种具有选择性的二肽基肽酶 4 (DPP-4) 抑制剂,具有抗糖尿病活性,可用于研究2 型糖尿病。 | |||
T7369 |
Gemigliptin
吉格列汀酒石酸盐,LC15-0444 |
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Gemigliptin (LC15-0444) 是一种选择性的,可逆的,竞争性的二肽基肽酶 4 (DPP-4) 抑制剂,对人重组 DPP-4 的 IC50=10.3 nM。Gemigliptin 具有很强的抗糖基化活性,能够用于晚期糖基化终产物相关的糖尿病并发症的研究。 | |||
T0191 |
Linagliptin
BI 1356,利格列汀,利拉利汀 |
Ferroptosis; Proteasome; DPP-4; Autophagy | Apoptosis; Autophagy; Proteases/Proteasome; Ubiquitination |
Linagliptin (BI 1356) 是一种有效的、可口服的、基于二氢嘌呤二酮的二肽基肽酶 4 抑制剂,具有降血糖活性。 | |||
T73151 |
USP22-IN-1
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
USP22-IN-1是一种泛素特异性肽酶22(USP22)抑制剂,可用于治疗增殖性疾病或癌症。 | |||
T23358 |
Sitagliptin phosphate
磷酸西他列汀,Januvia,MK-0431 phosphate,Sitagliptin (phosphate) |
DPP-4; Autophagy | Autophagy; Proteases/Proteasome |
Sitagliptin phosphate (MK-0431 phosphate) 是一种二肽基肽酶 4 (DPP4) 抑制剂,在 Caco-2 细胞中,IC50值为 19 nM。 | |||
T2296 |
Trelagliptin succinate
曲格列汀琥珀酸盐,琥珀酸曲格列汀,SYR-472 succinate,SYR472 |
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Trelagliptin succinate (SYR-472 succinate) 是一种有效的,具有口服活性的DPP-4抑制剂,IC50=4 nM。它可以改善体内血糖控制,能够用于2 型糖尿病(T2DM) 的研究。 | |||
T6999 |
Teneligliptin hydrobromide
Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide) |
Others; Proteasome; DPP-4 | Others; Proteases/Proteasome; Ubiquitination |
Teneligliptin hydrobromide (MP-513(hydrobromide)) 是β2肾上腺素能受体 (β2AR) 阻滞剂,具有抗高血压、抗氧化、清除自由基的活性。 | |||
T7369L |
Gemigliptin Tartrate(911637-19-9 free base)
吉格列汀酒石酸盐,LC15-0444 tartrate |
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Gemigliptin Tartrate (LC15-0444 tartrate) 是一种选择性的,可逆的,竞争性的二肽基肽酶 4 (DPP-4) 抑制剂,对于人重组 DPP-4 的IC50=10.3 nM。Gemigliptin tartrate 具有很强的抗糖基化活性,能够用于晚期糖基化终产物相关的糖尿病并发症的研究。 | |||
T1502 |
Vildagliptin
维达列汀,NVP-LAF 237,维格列汀,LAF237 |
Apoptosis; Ferroptosis; Proteasome; DPP-4 | Apoptosis; Proteases/Proteasome; Ubiquitination |
Vildagliptin (LAF237) 是一种选择性二肽基肽酶IV (DPP-IV) 抑制剂,在人 Caco-2 细胞中抑制 DPP-IV 的IC50为 3.5 nM。它具有出色的口服生物利用度和降血糖活性。 | |||
T78223 |
γ-Glu-Tyr
gamma-Glutamyltyrosine,gamma-GLU-TYR |
||
γ-Glu-Tyr (gamma-Glutamyltyrosine) 是一种对二肽基肽酶-IV (DPP-IV) 具有竞争性抑制作用的 kokumi 肽,可用于研究糖尿病。 | |||
TQ0038 |
Brensocatib
AZD7986,INS 1007 |
Proteasome | Proteases/Proteasome; Ubiquitination |
Brensocatib (AZD7986) 是一种二肽基肽酶 1 (DPP1) 抑制剂,在人,小鼠,大鼠,狗和兔中的pIC50分别为 6.85, 7.6, 7.7, 7.8 和 7.8。 | |||
T68053 |
Denagliptin
GW823093 |
DPP-4 | Proteases/Proteasome |
Denagliptin是一种小分子二肽基肽酶IV(DPP-4)抑制剂,可用于治疗内分泌于代谢疾病,可用于研究2型糖尿病。 | |||
T8550 |
NDMC101
|
Others; NF-κB; Proteasome | NF-κB; Others; Proteases/Proteasome; Ubiquitination |
NDMC101 是有效的破骨细胞形成抑制剂,通过下调 NFATc1 调控基因表达抑制破骨细胞分化。它与 DPP4底物相似,通过抑制DPP4抑制早期 T 细胞激活。它能够用于骨疾病的研究,如类风湿关节炎、滑膜炎等。 | |||
T5461 |
GNE-6640
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
GNE 6640 是一种选择性泛素特异性肽酶 7(USP7)的非共价抑制剂,其对全长USP7、USP7 催化结构域、全长USP43 以及 Ub-MDM2 的IC50值分别为 0.75 μM、0.43 μM、20.3 μM 和 0.23 μM。 | |||
T21979 |
P32/98 hemifumarate
P32/98 (hemifumarate)(136259-20-6 free base) |
DPP-4 | Proteases/Proteasome |
P32/98 hemifumarate 是一种二肽基肽酶 IV (DPP4) 抑制剂,具有降血糖作用,可在 Zucker 糖尿病大鼠模型中可改善胰岛素敏感性和 β 细胞反应性,可用于研究2型糖尿病和结肠炎。 | |||
T0242 |
Sitagliptin
西他列汀,MK0431,西格列汀 |
Proteasome; DPP-4; Autophagy | Autophagy; Proteases/Proteasome; Ubiquitination |
Sitagliptin (MK0431) 是一种有效的 DPP4抑制剂,在 Caco-2 细胞中,IC50值为 19 nM。它是一种新型口服降糖药,可单独使用或与二甲双胍或噻唑烷二酮联合用于治疗 2 型糖尿病。 | |||
T36352 |
Suc-Leu-Tyr-AMC
|
||
Suc-Leu-Tyr-AMC 是钙蛋白酶 I 和 II 以及木瓜蛋白酶(另一种半胱氨酸蛋白酶)的荧光底物,用于测量 20S 蛋白酶体的糜蛋白酶样肽酶活性(Ex-max:360 nm;Em-max:460 nm)。Suc-Leu-Tyr-AMC 也能被大肠杆菌的 Ti 蛋白酶裂解。 | |||
T70254 |
FE-999011
|
||
FE-999011 is a dipeptidyl peptidase IV inhibitor. | |||
T26769 |
Benarthin
|
||
Benarthin is a pyroglutamyl peptidase (PG-peptidase) inhibitor. | |||
T26850 |
BMS-538305 HCl
BMS-538305,BMS538305,BMS 538305,BMS-538305 hydrochloride |
||
BMS-538305 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP-IV). | |||
T25382 |
Epostatin
|
||
Epostatin is a new dipeptidyl peptidase II (DPP-II, EC 3.4.14.2) inhibitor. | |||
T27353 |
Fotagliptin
|
||
Fotagliptin is a dipeptidyl peptidase IV inhibitor. | |||
T10082 |
DPP-IV-IN-1
|
Others | Others |
DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM). | |||
T11049 |
Diprotin A TFA
Ile-Pro-Pro (TFA) |
Others | Others |
Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV). | |||
T31378 |
Denagliptin tosylate
GSK-823093,GSK 823093,GW-823093,GW 823093,GSK823093,GW823093 |
||
Denagliptin (GW823093 or GSK-823093) is a dipeptidyl peptidase IV (DPP-IV) inhibitor. | |||
T68561 |
ASP-4000 free base
|
||
ASP-4000 free base is a dipeptidyl peptidase 4 (DPP) inhibitor with antihyperglycemic activity. | |||
T25341 |
Diprotin B
|
||
Diprotin B is a dipeptidyl peptidase IV inhibitor. | |||
T22886 |
K 579
|
Others | Others |
K 579 is a dipeptidyl peptidase IV inhibitor. | |||
T71117 |
AZD5248
|
||
AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1). | |||
T12989 |
SPL-410
|
Others | Others |
SPL-410 is a highly potent,selective and orally active inhibitor of hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a)(IC50 of 9 nM). | |||
T68652 |
Carmegliptin dihydrochloride
|
||
Carmegliptin dihydrochloride is the salt form of Camegliptin (free base), also known as RG-1579 and RO4876904, a dipeptidyl peptidase IV (DPP-4) inhibitor potentially for the treatment of type 2 diabetes. | |||
T11248 |
Evogliptin tartrate
DA-1229 tartrate |
DPP-4 | Proteases/Proteasome |
Evogliptin tartrate has potential for anti-atherosclerosis therapy that targets arterial inflammation. Evogliptin tartrate is a potent, orally bioavailable and selective dipeptidyl peptidase-4 (DPP-4) inhibitor, with antidiabetic activity. | |||
T11450 |
Gosogliptin
PF-00734200,PF-734200 |
Others | Others |
Gosogliptin is a potent and selective dipeptidyl peptidase-IV (DPP-IV) inhibitor. | |||
T70518 | CGP-53437 | ||
CGP-53437 is a novel HIV-1 protease inhibitor, also potently inhibiting major aspartyl peptidase 1 (May1), a secreted Cryptococcus neoformans protease. | |||
T26941 |
Camegliptin
RO-4876904-001,R1579,RG1579,RO-4876904,R-1579,RG-1579 |
||
Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes. | |||
T36338 |
AAF-CMK (trifluoroacetate salt)
|
||
Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at 50 μM. | |||
T62019 | Sheng Gelieting | ||
Sheng Gelieting (CGT-8012) 是二肽基肽酶-IV 酶(DP-IV)抑制剂,IC50值为 87 nM。Sheng Gelieting 可用于研究二肽基肽酶-IV 酶相关的疾病,如糖尿病,特别是 II 型糖尿病。 | |||
TP2144 |
Globomycin
|
Others | Others |
Globomycin is a lipopeptide antibiotic and an inhibitor of signal peptidase II (LspA). It inhibits the processing of the prolipoprotein by binding irreversibly to the peptidase. | |||
T71831 |
L-Ornithine lactam hydrochloride
|
||
L-Ornithine lactam is a synthetic intermediate. It has been used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides. | |||
T27598 |
Imigliptin Dihydrochloride
Imigliptin |
||
Imigliptin Dihydrochloride, a selective dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type II diabetes. | |||
T68863 | MK-0626 free base | ||
MK-0626 is a Dipeptidyl peptidase IV (DPP-4) inhibitor, improving neovascularization by increasing both the number of circulating endothelial progenitor cells and endothelial nitric oxide synthetase expression. | |||
T79911 |
O-Benzoylhydroxylamine
|
||
O-Benzoyloxyamine 为一种DPP-IV 抑制剂,具备抗糖尿病功能。 | |||
TP2357 |
Ularitide
CDD 95-126,ANP 95-126,Human urodilatin |
||
Ularitide is a 32-amino acid peptide derived from (95-126 residues) of ANP PROHORMONE (1-126 residues). It isn't biologically inactivated by a peptidase from dog kidney cortex membranes. | |||
T63698 |
PK44 phosphate
|
||
PK44 phosphate 是二肽基肽酶 IV (DPP-IV) 的有效抑制剂 (IC50: 15.8 nM)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16838 |
Saikogenin A
|
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Saikogenin A 是一种二肽基肽酶 IV 抑制剂,可从中药柴胡中提取。 | |||
TN1418 |
Azaleatin
杜鹃黄素,2-(3,4-二羟基苯基)-3,7-二羟基-5-甲氧基苯并吡喃-4-酮 |
DPP-4 | Proteases/Proteasome |
Azaleatin 是分离自Rhododendron 种中的 O-甲基化黄酮醇。它是二肽基肽酶-IV 的抑制剂。它在 2 型糖尿病和肥胖症中有研究的价值。 | |||
T19503 |
Papain
|
Others; Cysteine Protease | Others; Proteases/Proteasome |
Papain 是一种半胱氨酸蛋白酶,是肽酶 C1 家族中一员,在食品、医药、化妆品、纺织等具有广泛的应用。 | |||
T75493 | Ellipyrone B | ||
Ellipyrone B,一种大环肽,对二肽基肽酶 4 (dipeptidyl peptidase-4: IC50=0.48 mM) 表现出抑制作用。 | |||
T75492 | Ellipyrone A | ||
Ellipyrone A为一种大环肽,对二肽基肽酶 4 (dipeptidyl peptidase-4: IC50=0.35 mM) 显示出抑制活性,并对α-葡萄糖苷酶 (IC50=0.74 mM) 及α-淀粉酶 (IC50=0.59 mM) 也具有明显的抑制效果,表现出其抗碳水化合物分解的性能。 | |||
T83863 |
Fluostatin A sodium
|
||
Fluostatin A是一种最初从链霉菌中分离出的荧光酮类化合物。它对二肽基肽酶3(DPP-3)的选择性抑制作用优于对DPP-1、DPP-2和DPP-4的抑制作用(IC50s分别为0.44, >100, >100, 和 >100 µg/ml)。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00915 |
Serpin A1 Protein, Human, Recombinant (His)
PRO2275,SerpinA1,serpin peptidase... |
Human | HEK293 Cells |
Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1. | |||
TMPY-04501 |
Angiotensinogen Protein, Rat, Recombinant (His)
angiotensinogen (serpin peptidase... |
Rat | HEK293 Cells |
Angiotensinogen Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A6KJ10. | |||
TMPY-00442 |
Serpin A1 Protein, Rat, Recombinant (His)
SerpinA1,serpin peptidase inhibit... |
Rat | HEK293 Cells |
Serpin A1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.2 kDa and the accession number is A0A0G2JY31. | |||
TMPY-04934 |
Serpin A3n Protein, Rat, Recombinant (His)
serine (or cysteine) peptidase inhibitor, ... |
Rat | HEK293 Cells |
Serpina3n may represent a circulating biomarker of muscle atrophy associated with GC and, broadly, a reflection of dynamic changes in muscle mass. Serpina3n blocks endogenous increases in the activity of select skeletal muscle resident proteases during injury or dystrophic disease, which stabilizes the sarcolemma leading to less myofiber degeneration and increased regeneration. | |||
TMPY-01232 |
Angiotensinogen Protein, Human, Recombinant (His)
SERPINA8,angiotensinogen (serpin pepti... |
Human | HEK293 Cells |
Angiotensinogen Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.2 kDa and the accession number is B0ZBE2. | |||
TMPY-01363 |
Serpin A11 Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade... |
Mouse | HEK293 Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi... | |||
TMPY-05329 |
Cortisol Binding Globulin Protein, Human, Recombinant (His & Avi), Biotinylated
serpin peptidase inhibitor, clade... |
Human | HEK293 Cells |
Cortisol Binding Globulin Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.9 kDa and the accession number is A0A2Z4LCH4. | |||
TMPY-02041 |
Cortisol Binding Globulin Protein, Human, Recombinant (His)
CBG,serpin peptidase inhibitor, cla |
Human | HEK293 Cells |
Cortisol Binding Globulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44 kDa and the accession number is A0A2Z4LCH4. | |||
TMPY-02232 |
Angiotensinogen Protein, Mouse, Recombinant (His)
AngI,Serpina8,angiotensinogen (se... |
Mouse | HEK293 Cells |
Angiotensinogen Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is P11859. | |||
TMPY-01855 |
Serpin A10 Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade... |
Mouse | HEK293 Cells |
Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPINA1 / Serpin-A1 inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because ... | |||
TMPY-01893 |
Serpin A12 Protein, Human, Recombinant (His)
OL-64,serpin peptidase inhibitor, cla<... |
Human | HEK293 Cells |
Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin, in egg white), hormone carriage proteins (thyroxine-binding globulin, cortisol-binding globulin) and tumor suppressor genes (maspin). Most inhibitory serpins target chymotrypsin-like serine proteases. These enzymes are defined by the presence of a nucleophilic serine residue in ... | |||
TMPY-01256 |
TBG Protein, Human, Recombinant (His)
Serpin A7,serpin peptidase inhibi... |
Human | HEK293 Cells |
TBG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.5 kDa and the accession number is P05543. | |||
TMPY-01240 |
TBG Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade... |
Mouse | HEK293 Cells |
TBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.2 kDa and the accession number is Q3UEL9. | |||
TMPY-02107 |
Cortisol Binding Globulin Protein, Mouse, Recombinant (His)
SerpinA6,AV104445,AI265318,serpin... |
Mouse | HEK293 Cells |
Cortisol Binding Globulin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is Q06770. | |||
TMPY-06702 |
Cortisol Binding Globulin Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cbg,AI265318,serpin peptidase inh... |
Mouse | HEK293 Cells |
Cortisol Binding Globulin Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.54 kDa and the accession number is Q06770. | |||
TMPY-01303 |
Serpin A3 Protein, Human, Recombinant (His)
ACT,GIG25,serpin peptidase inhibi... |
Human | HEK293 Cells |
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzy... | |||
TMPY-02712 |
Serpin B3 Protein, Human, Recombinant (His)
T4-A,HsT1196,serpin peptidase inh... |
Human | Baculovirus Insect Cells |
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be... | |||
TMPY-01398 |
Alpha 2 Antiplasmin/SerpinF2 Protein, Human, Recombinant (His)
serpin peptidase inhibitor, clade... |
Human | HEK293 Cells |
Alpha 2 Antiplasmin/SerpinF2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.2 kDa and the accession number is P08697-1. | |||
TMPY-01329 |
Serpin A3c Protein, Mouse, Recombinant (His)
MGC144822,serine (or cysteine) peptidase i... |
Mouse | HEK293 Cells |
Serpin A3c Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P29621. | |||
TMPY-00623 |
Serpin A1d Protein, Mouse, Recombinant
PI4,serine (or cysteine) peptidase inhibit... |
Mouse | HEK293 Cells |
Serpin A1d Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 44.1 kDa and the accession number is XP_003945711.1. | |||
TMPY-00621 |
Serpin A1d Protein, Mouse, Recombinant (His)
AI118301,Serpin A1d,Spi1-4,PI4,Dom4,serine... |
Mouse | HEK293 Cells |
Serpin A1d Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is XP_003945711.1. | |||
TMPY-00619 |
Serpin A1d Protein, Mouse, Recombinant (hFc)
Spi1-4,PI4,Serpin A1d,serine (or cysteine) pept... |
Mouse | HEK293 Cells |
Serpin A1d Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is XP_003945711.1. | |||
TMPH-01199 |
CNDP2 Protein, Human, Recombinant (E. coli, His)
HEL-S-13,CPGL,Threonyl dipeptidase,PEP... |
Human | E. coli |
CNDP2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPJ-00929 |
Serpin B3 Protein, Human, Recombinant (N-His)
SCCA-1,Serpin B3,serine (or cysteine) proteina<... |
Human | E. coli |
Serpin B3 Protein, Human, Recombinant (N-His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40-55 KDa and the accession number is P29508. | |||
TMPJ-00928 |
Serpin B3 Protein, Human, Recombinant (C-His)
SCCA1,serpin peptidase inhibitor,... |
Human | HEK293 Cells |
Serpin B3 Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 41-50 KDa and the accession number is P29508. | |||
TMPH-00067 |
Venom dipeptidyl peptidase 4 Protein, Apis mellifera, Recombinant (His & Myc)
|
Apis mellifera | E. coli |
Venom dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. May process promelittin into its active form and/or modulate the chemotactic activity of immune cells after the insect sting. Venom dipeptidyl peptidase 4 Protein, Apis mellifera, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.4 kDa and the... | |||
TMPY-02258 |
Kallikrein 3/KLK3 Protein, Human, Recombinant (His)
APS,KLK2A1,PSA,kallikrei... |
Human | HEK293 Cells |
KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases.... | |||
TMPY-01897 |
PRSS3 Protein, Human, Recombinant (His)
PRSS4,TRY4,TRY3,RP11-176F3.3,T9,MTG,protease, serin... |
Human | HEK293 Cells |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ... | |||
TMPY-01460 |
ABHD4 Protein, Human, Recombinant (His)
abhydrolase domain conta... |
Human | Baculovirus Insect Cells |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa... | |||
TMPY-02078 |
HtrA2/Omi Protein, Human, Recombinant (His)
PARK13,OMI,HtrA serine peptida |
Human | E. coli |
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the peptidase S1B family. HTRA2 contains one PDZ (DHR) domain. HTRA2 is a serine protease that shows proteolytic activity against a non-specific substrate beta-casein. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor... | |||
TMPJ-00375 |
HGF Protein, Human, Recombinant (His)
Scatter factor,Hepatocyte growth ... |
Human | HEK293 Cells |
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelia... | |||
TMPY-02869 |
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptid... |
Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... | |||
TMPJ-00481 |
CELA3A Protein, Human, Recombinant (His)
Elastase-3A,ELA3A |
Human | HEK293 Cells |
Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. ELA3A may also function in the intestinal transport and metabolism of cholesterol. ELA3A is efficient protease with alanine specificity but only little e... | |||
TMPJ-01203 |
HATL5 Protein, Human, Recombinant (His)
HATL5,Transmembrane Protea |
Human | HEK293 Cells |
Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease that may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. | |||
TMPY-01854 |
DPP10 Protein, Human, Recombinant (His)
DPPY,DPRP3,DPRP-3,DPL2,dipeptidyl-peptidase |
Human | HEK293 Cells |
Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein which belongs to thepeptidase S9B family.DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP1 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally p... | |||
TMPJ-00891 |
Kallikrein 2/KLK2 Protein, Human, Recombinant (His)
hGK-1,Kallikrein-2,Tissue Kallikrein-2,KLK... |
Human | HEK293 Cells |
Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 ... | |||
TMPJ-01008 |
THOP1 Protein, Human, Recombinant (His)
THOP1,MP78,Thimet Oligopeptidase,Endop... |
Human | E. coli |
Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degrada... | |||
TMPK-00377 |
DPPIV/CD26 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
DPP4,DPPIV,ADCP2,CD26,ADABP,TP103... |
Cynomolgus,Rhesus | HEK293 Cells |
CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express DPPIV/CD26 to a variable extent. | |||
TMPJ-00497 |
CTSB Protein, Human, Recombinant (His)
APPS,CPSB,APP Secretase,Ca |
Human | HEK293 Cells |
Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor... | |||
TMPJ-00707 |
Coagulation factor X/F10 Protein, Mouse, Recombinant (His)
Stuart factor,Coagulatio... |
Mouse | HEK293 Cells |
Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin K-dependent plasma protease that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. The two chains of F10 are formed from a single-chain precursor by the excision of two Arg residues. A single-chain precursor is initiall... | |||
TMPJ-00942 |
MMP-12 Protein, Mouse, Recombinant (His)
Mme,Mmp12,MMP-12,Mmel,Matrix metalloprotei... |
Mouse | HEK293 Cells |
Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. | |||
TMPH-00866 |
ADAMTS14 Protein, Human, Recombinant (His)
A disintegrin and metalloprotein<... |
Human | E. coli |
Has aminoprocollagen type I processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity. Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form. ADAMTS14 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.2 kDa and the accession number is Q8WXS8. | |||
TMPJ-00540 |
PEPD Protein, Human, Recombinant
PRD,Imidodipeptidase,PEPD,Peptida<... |
Human | E. coli |
PEPD belongs to the peptidase M24B family of Eukaryotic-type prolidase subfamily. PEPD is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus. It is important in collagen metabolism because of the high levels of imino acids. Defects in PEPD are a cause of prolidase deficiency which is an autosomal recessive disorder associated with iminodipeptiduria. | |||
TMPY-02759 |
Kallikrein 6/KLK6 Protein, Human, Recombinant (His)
kallikrein-related peptidase<... |
Human | HEK293 Cells |
KLK6 (kallikrein-related peptidase 6), also known as Klk7, belongs to the peptidase S1 family, Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK6 is a serine protease that exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Klk7 sh... | |||
TMPY-00732 |
Cathepsin C Protein, Human, Recombinant (His)
DPP-I,PLS,JP,cathepsin C,CPPI,DPPI,PDON1,PA |
Human | HEK293 Cells |
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active c... | |||
TMPJ-01393 |
PGCP Protein, Mouse, Recombinant (His)
Plasma glutamate ca<... |
Mouse | HEK293 Cells |
Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides with unsubstituted terminals into amino acids. Carboxypeptidase may play an important role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor. The monomeric form is inactive while the homodimer is active. | |||
TMPJ-00902 |
Kell Protein, Human, Recombinant (His)
CD238,KEL,Kell blood group glycoprotein |
Human | HEK293 Cells |
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that car... | |||
TMPJ-01336 |
SENP2 Protein, Human, Recombinant
Sentrin/SUMO-specific protease SENP2,Ax |
Human | E. coli |
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. | |||
TMPJ-01350 |
XPNPEP3 Protein, Human, Recombinant (His)
XPNPEP3,X-Pro Aminopeptidase 3, |
Human | E. coli |
Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-s... | |||
TMPJ-00332 |
tPA Protein, Human, Recombinant (His)
TPA,T-PA,t-plasminogen a... |
Human | HEK293 Cells |
Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, PLAT plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and in modulating the post-tra... | |||
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